Untreatable Gonorrhea – The Next Infectious Threat

Our old nemesis, the clap, is in the news again this month. Gonorrhea is the second most common sexually transmitted disease in the US, with more than 600,000 cases annually. In men it usually causes pain on urination, penile discharge, or sore throat. In women it may not cause symptoms or may cause painful urination, vaginal discharge, or sore throat. If untreated, gonorrhea can spread to the fallopian tubes, joints, and heart valves. I know that most readers simply can’t hear enough about p...
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Relearning What We Knew: Antibiotics Don’t Help In Sinus Infections

Most of us are personally familiar with the symptoms of a sinus infection – congested nose, cough, fever, pain in the forehead or cheeks, and general misery. It’s impossible not to feel sympathetic for patients with sinus infections, and it’s understandable that they want to do whatever it takes to feel better as soon as possible. And for many doctors and patients “as soon as possible” means “antibiotics”. In fact, almost one fifth of antibiotic prescriptions are given for patients with sinus ...
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Major Study Examines Causes of Morgellons

The name Morgellons originated in 2002. That year a mother took her young son to doctors reporting that he was complaining of “bugs” in his skin. He had sores under his lips and the mother reported seeing fibers in these sores. She named her son’s illness Morgellons and started a website to raise awareness and research funding for the disorder. The boy’s doctors found no specific abnormality and believed that the mother was suffering from a psychiatric condition. Since then many patients have p...
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Don’t Put Unsterilized Tap Water Up Your Nose

I like introducing you periodically to some of the stranger and more dangerous germs out there. It’s a good reminder that nature isn’t just full of daisies and rainbows, and that the most lethal dangers we face are natural. This week’s news presents a terrific example. Meet Naegleria fowleri. Naegleria fowleri is an amoeba, a single celled parasite that lives in warm bodies of fresh water, like lakes and rivers. Its nickname is the brain-eating amoeba. Isn’t that nice? (My nic...
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Ivacaftor – a Breakthrough in Cystic Fibrosis Treatment

One of the implicit themes we were taught in medical school is that an understanding of the basic science of a disease informs and guides treatment of patients. The general philosophy that we absorbed was that an understanding of the molecular or cellular defects in a disease would explain the abnormal organ physiology which would explain the patient’s abnormal signs and symptoms. This understanding of the abnormality at a molecular or cellular level would also help discover medications that cor...
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Contaminated Cantaloupes Responsible for Listeria Outbreak

My regular readers know I have a bit of an obsession with food-borne illness. Why? Because it’s such a difficult and old problem. (Obviously germs have been contaminating food and sickening animals long before people were around.) Modern sanitation and farming have made our food much safer, but occasional outbreaks remind us that our current methods are still imperfect. This week an outbreak of the bacterium Listeria has sickened over 20 people in seven states. (California has not been affected...
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