Amyotrophic lateral sclerosis (ALS, sometimes called Lou Gehrig’s disease) is a truly horrible illness. It is a progressive fatal neurodegenerative disorder that leads to worsening muscle weakness.
Weakness in the limbs initially makes handwriting sloppy and makes it hard to button clothes and eventually causes paralysis. Patients also develop weakness in the muscles that control swallowing and speech, eventually requiring them to use feeding tubes and computer text-to-speech software. Ev...
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A Small Step Towards An Artificial Pancreas
Patients with type 1 diabetes (T1D) are forced to spend much of their time obsessing about their blood sugar and insulin doses. The state of the art in treatment of T1D is an insulin pump that delivers insulin and a continuous glucose monitor that displays the glucose level and sounds alarms for values that are too low or too high. (See here for a refresher on the differences between type 1 and type 2 diabetes.)
Currently, p...
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There Has Never Been a Better Time to Have Diabetes
The danger of diabetes is not only the immediate risk of very high blood sugar. Diabetes also has many dreaded long-term complications. (In this post I am referring to both type 1 and type 2 diabetes mellitus. For an explanation of the differences between these two very different diseases see the first half of this post.) Diabetes greatly increases the risk of stroke, heart attack, and amputation. In the US it is the leadin...
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New Cholesterol Treatment Recommendations
This week the American College of Cardiology and the American Heart Association released new guidelines for the treatment of high cholesterol. These new guidelines represent a revolutionary change i...
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Weight Loss Doesn’t Decrease Strokes and Heart Attacks in Overweight Diabetics
Doctors spend a lot of time recommending diet and exercise for weight loss. If you’re my patient, unless you’re quite fit, you've probably heard me ask you to exercise more and eat less. There is good reason for this. Many short term studies hav...
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Are You Obese?
Americans are getting heavier and have been doing so for decades. One in three adults in the US is obese. Overweight and obese people are more likely to develop diabetes, high blood pressure, heart disease, and other serious health problems. What can be done?
Last month the ...
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A New Weight Loss Drug is Closer to FDA Approval
The current range of options for medications for weight loss is not encouraging. The only medication approved by the FDA for long-term use for weight loss is orlistat, available over the counter by the brand name Alli, or Xenical by prescription. It is only modestly effec...
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Weight-Loss Surgery More Effective for Diabetes than Medication
About 20 million Americans currently have type 2 diabetes, three times more than in 1980. Diabetes is a major risk factor for stroke and heart attack, is the leading cause of new cases of blindness, and is the largest cause of the need for dialysis. Diabetes is also usually progressive, meaning that on the same medications and on the same diet and exercise regimen, the blood sugar of a patient with diabetes will slowly increase, necessitating constantly increasing amounts of medications.
So des...
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Amputations in Diabetics Decline Dramatically
Diabetes can lead to numerous serious complications. It is a major risk factor for stroke and heart attack. Diabetes can damage the retina and is the leading cause of new cases of blindness in the US. It can damage the kidneys and is the greatest cause of need for dialysis. It can also cause nerve damage...
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News Flash: Diabetes is Not Good
Type 2 diabetes mellitus has long been known to increase the risk of stroke, heart attack, kidney disease, and eye disease. In the US diabetes is the leading cause of kidney failure requiring dialysis and one of the leading causes of blindness. Diabetes is also increasing in prevalence as people become more overweight.
A study in this week’s New England Journal of Medicine attempted to quantify the risk of premature death associated with diabetes. The results were dramatic, and attracted much m...
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